{"ticker":"XBI","name":"SPDR S&P Biotech ETF","as_of":"2026-08-25","source":"issuer_daily","source_status":"ok","checked_at":"2026-08-27T04:26:35+00:00","holdings":{"60770K107":{"n":"Moderna Inc","t":"MRNA","w":3.0533},"90184D100":{"n":"Twist Bioscience Corp","t":"TWST","w":1.9753},"03770N101":{"n":"Apogee Therapeutics Inc","t":"APGE","w":1.4412},"501575104":{"n":"Kymera Therapeutics Inc","t":"KYMR","w":1.4312},"687604108":{"n":"Oruka Therapeutics Inc","t":"ORKA","w":1.4058},"632307104":{"n":"Natera Inc","t":"NTRA","w":1.3751},"40637H109":{"n":"Halozyme Therapeutics Inc","t":"HALO","w":1.371},"74006W207":{"n":"Praxis Precision Medicines I","t":"PRAX","w":1.3518},"252828108":{"n":"Dianthus Therapeutics Inc","t":"DNTH","w":1.2972},"76155X100":{"n":"Revolution Medicines Inc","t":"RVMD","w":1.296},"156944100":{"n":"Cg Oncology Inc","t":"CGON","w":1.271},"89422G107":{"n":"Travere Therapeutics Inc","t":"TVTX","w":1.2675},"00773J202":{"n":"Spyre Therapeutics Inc","t":"SYRE","w":1.2643},"74366E102":{"n":"Protagonist Therapeutics Inc","t":"PTGX","w":1.2589},"75886F107":{"n":"Regeneron Pharmaceuticals","t":"REGN","w":1.2246},"457669307":{"n":"Insmed Inc","t":"INSM","w":1.1921},"92243G108":{"n":"Vaxcyte Inc","t":"PCVX","w":1.1892},"29479A108":{"n":"Erasca Inc","t":"ERAS","w":1.1744},"76243J105":{"n":"Rhythm Pharmaceuticals Inc","t":"RYTM","w":1.1692},"80706P103":{"n":"Scholar Rock Holding Corp","t":"SRRK","w":1.1681},"031162100":{"n":"Amgen Inc","t":"AMGN","w":1.1579},"75943R102":{"n":"Relay Therapeutics Inc","t":"RLAY","w":1.1516},"G76279101":{"n":"Roivant Sciences Ltd","t":"ROIV","w":1.135},"92532F100":{"n":"Vertex Pharmaceuticals Inc","t":"VRTX","w":1.1211},"04280A100":{"n":"Arrowhead Pharmaceuticals In","t":"ARWR","w":1.1111},"H17182108":{"n":"Crispr Therapeutics Ag","t":"CRSP","w":1.0892},"92686J106":{"n":"Viking Therapeutics Inc","t":"VKTX","w":1.0887},"45337C102":{"n":"Incyte Corp","t":"INCY","w":1.0884},"462260100":{"n":"Iovance Biotherapeutics Inc","t":"IOVA","w":1.0882},"N90064101":{"n":"Uniqure Nv","t":"QURE","w":1.0864},"81642T209":{"n":"Sellas Life Sciences Group I","t":"SLS","w":1.0827},"375558103":{"n":"Gilead Sciences Inc","t":"GILD","w":1.082},"004225108":{"n":"Acadia Pharmaceuticals Inc","t":"ACAD","w":1.0796},"10806X102":{"n":"Bridgebio Pharma Inc","t":"BBIO","w":1.0546},"88322Q108":{"n":"Tg Therapeutics Inc","t":"TGTX","w":1.0511},"384747101":{"n":"Grail Inc","t":"GRAL","w":1.0449},"00287Y109":{"n":"Abbvie Inc","t":"ABBV","w":1.0438},"09061G101":{"n":"Biomarin Pharmaceutical Inc","t":"BMRN","w":1.0408},"19240Q201":{"n":"Cogent Biosciences Inc","t":"COGT","w":1.0369},"23282W605":{"n":"Cytokinetics Inc","t":"CYTK","w":1.0212},"501147102":{"n":"Krystal Biotech Inc","t":"KRYS","w":1.0083},"09062X103":{"n":"Biogen Inc","t":"BIIB","w":1.005},"45258J102":{"n":"Immunovant Inc","t":"IMVT","w":0.9953},"G01767105":{"n":"Alkermes Plc","t":"ALKS","w":0.9925},"26818M108":{"n":"Dyne Therapeutics Inc","t":"DYN","w":0.9711},"558868105":{"n":"Madrigal Pharmaceuticals Inc","t":"MDGL","w":0.9597},"30161Q104":{"n":"Exelixis Inc","t":"EXEL","w":0.9529},"07373V105":{"n":"Beam Therapeutics Inc","t":"BEAM","w":0.9296},"15102K100":{"n":"Celcuity Inc","t":"CELC","w":0.9238},"604749101":{"n":"Mirum Pharmaceuticals Inc","t":"MIRM","w":0.9226},"45256X103":{"n":"Immunitybio Inc","t":"IBRX","w":0.908},"69366J200":{"n":"Ptc Therapeutics Inc","t":"PTCT","w":0.8849},"86627T108":{"n":"Summit Therapeutics Inc","t":"SMMT","w":0.8842},"45166A102":{"n":"Ideaya Biosciences Inc","t":"IDYA","w":0.873},"90400D108":{"n":"Ultragenyx Pharmaceutical In","t":"RARE","w":0.8608},"64125C109":{"n":"Neurocrine Biosciences Inc","t":"NBIX","w":0.8424},"91307C102":{"n":"United Therapeutics Corp","t":"UTHR","w":0.8422},"92790C104":{"n":"Viridian Therapeutics Inc","t":"VRDN","w":0.8415},"09058V103":{"n":"Biocryst Pharmaceuticals Inc","t":"BCRX","w":0.8356},"92337R101":{"n":"Vera Therapeutics Inc","t":"VERA","w":0.8295},"45257U108":{"n":"Immunome Inc","t":"IMNM","w":0.7821},"24823R105":{"n":"Denali Therapeutics Inc","t":"DNLI","w":0.7687},"462222100":{"n":"Ionis Pharmaceuticals Inc","t":"IONS","w":0.7659},"803607100":{"n":"Sarepta Therapeutics Inc","t":"SRPT","w":0.7487},"15117B202":{"n":"Celldex Therapeutics Inc","t":"CLDX","w":0.7408},"02043Q107":{"n":"Alnylam Pharmaceuticals Inc","t":"ALNY","w":0.7282},"03969F109":{"n":"Arcus Biosciences Inc","t":"RCUS","w":0.7247},"254604101":{"n":"Disc Medicine Inc","t":"IRON","w":0.7007},"75629V104":{"n":"Recursion Pharmaceuticals A","t":"RXRX","w":0.6991},"45826J105":{"n":"Intellia Therapeutics Inc","t":"NTLA","w":0.69},"000899104":{"n":"Adma Biologics Inc","t":"ADMA","w":0.6719},"44916Y106":{"n":"Hyperliquid Strategies","t":"PURR","w":0.6684},"603170101":{"n":"Mineralys Therapeutics Inc","t":"MLYS","w":0.6591},"03969K108":{"n":"Arcutis Biotherapeutics Inc","t":"ARQT","w":0.6427},"87583X109":{"n":"Tango Therapeutics Inc","t":"TNGX","w":0.6353},"670002401":{"n":"Novavax Inc","t":"NVAX","w":0.6305},"87164F105":{"n":"Syndax Pharmaceuticals Inc","t":"SNDX","w":0.6234},"00847X104":{"n":"Agios Pharmaceuticals Inc","t":"AGIO","w":0.603},"67080M103":{"n":"Nurix Therapeutics Inc","t":"NRIX","w":0.5896},"92337F107":{"n":"Veracyte Inc","t":"VCYT","w":0.5846},"697947109":{"n":"Palvella Therapeutics Inc","t":"PVLA","w":0.539},"50015M109":{"n":"Kodiak Sciences Inc","t":"KOD","w":0.5249},"14167L103":{"n":"Caredx Inc","t":"CDNA","w":0.5167},"98401F105":{"n":"Xencor Inc","t":"XNCR","w":0.5056},"230031106":{"n":"Cullinan Therapeutics Inc","t":"CGEM","w":0.4854},"G1110E107":{"n":"Biohaven Ltd","t":"BHVN","w":0.4849},"92764N102":{"n":"Vir Biotechnology Inc","t":"VIR","w":0.4712},"86150R107":{"n":"Stoke Therapeutics Inc","t":"STOK","w":0.4684},"92346J108":{"n":"Vericel Corp","t":"VCEL","w":0.4592},"74017N105":{"n":"Precigen Inc","t":"PGEN","w":0.4589},"00091E109":{"n":"Absci Corp","t":"ABSI","w":0.443},"45720N103":{"n":"Inhibrx Biosciences Inc","t":"INBX","w":0.4378},"032724106":{"n":"Anaptysbio Inc","t":"ANAB","w":0.4084},"98937L105":{"n":"Zenas Biopharma Inc","t":"ZBIO","w":0.4054},"68622P109":{"n":"Oric Pharmaceuticals Inc","t":"ORIC","w":0.4017},"76029N106":{"n":"Replimune Group Inc","t":"REPL","w":0.3861},"221015100":{"n":"Corvus Pharmaceuticals Inc","t":"CRVS","w":0.3797},"929033207":{"n":"Vor Biopharma Inc","t":"VOR","w":0.3751},"337185102":{"n":"First Tracks Biotherapeutics","t":"TRAX","w":0.3733},"50127T109":{"n":"Kura Oncology Inc","t":"KURA","w":0.3718},"05338F306":{"n":"Avalo Therapeutics Inc","t":"AVTX","w":0.3563},"90240B106":{"n":"Tyra Biosciences Inc","t":"TYRA","w":0.3306},"47103J105":{"n":"Janux Therapeutics Inc","t":"JANX","w":0.3205},"56400P706":{"n":"Mannkind Corp","t":"MNKD","w":0.3152},"877619106":{"n":"Taysha Gene Therapies Inc","t":"TSHA","w":0.307},"374163103":{"n":"Geron Corp","t":"GERN","w":0.3008},"008064206":{"n":"Jade Biosciences Inc","t":"JBIO","w":0.298},"03589W102":{"n":"Annexon Inc","t":"ANNX","w":0.2856},"61225M102":{"n":"Monte Rosa Therapeutics Inc","t":"GLUE","w":0.2738},"45258H106":{"n":"Immix Biopharma Inc","t":"IMMX","w":0.2709},"766559702":{"n":"Rigel Pharmaceuticals Inc","t":"RIGL","w":0.2704},"68062P106":{"n":"Olema Pharmaceuticals Inc","t":"OLMA","w":0.2637},"799566104":{"n":"Sana Biotechnology Inc","t":"SANA","w":0.2581},"039697107":{"n":"Ardelyx Inc","t":"ARDX","w":0.2494},"137404109":{"n":"Candel Therapeutics Inc","t":"CADL","w":0.2449},"04272N102":{"n":"Arrivent Biopharma Inc","t":"AVBP","w":0.2446},"055477103":{"n":"Bicara Therapeutics Inc","t":"BCAX","w":0.2398},"23284F105":{"n":"Cytomx Therapeutics Inc","t":"CTMX","w":0.2388},"019770106":{"n":"Allogene Therapeutics Inc","t":"ALLO","w":0.2344},"02155H200":{"n":"Altimmune Inc","t":"ALT","w":0.2305},"83422E204":{"n":"Solid Biosciences Inc","t":"SLDB","w":0.2272},"35104E100":{"n":"4D Molecular Therapeutics In","t":"FDMT","w":0.225},"46333X108":{"n":"Ironwood Pharmaceuticals Inc","t":"IRWD","w":0.2148},"92337C203":{"n":"Verastem Inc","t":"VSTM","w":0.2135},"G2646Y104":{"n":"Damora Therapeutics Inc","t":"DMRA","w":0.1947},"67577C105":{"n":"Ocugen Inc","t":"OCGN","w":0.1742},"74168J101":{"n":"Prime Medicine Inc","t":"PRME","w":0.1725},"03879J100":{"n":"Arbutus Biopharma Corp","t":"ABUS","w":0.17},"14070B309":{"n":"Capricor Therapeutics Inc","t":"CAPR","w":0.1602},"805111101":{"n":"Savara Inc","t":"SVRA","w":0.1592},"75901B107":{"n":"Regenxbio Inc","t":"RGNX","w":0.1553},"20454B104":{"n":"Compass Therapeutics Inc","t":"CMPX","w":0.1539},"12674W109":{"n":"Cabaletta Bio Inc","t":"CABA","w":0.1506},"690469101":{"n":"Ovid Therapeutics Inc","t":"OVID","w":0.1274},"G72800108":{"n":"Prothena Corp Plc","t":"PRTA","w":0.1218},"46489V302":{"n":"Perspective Therapeutics Inc","t":"CATX","w":0.1181},"82835W108":{"n":"Ars Pharmaceuticals Inc","t":"SPRY","w":0.1164},"602496101":{"n":"Mimedx Group Inc","t":"MDXG","w":0.1142},"921659108":{"n":"Vanda Pharmaceuticals Inc","t":"VNDA","w":0.1109},"52886X107":{"n":"Lexeo Therapeutics Inc","t":"LXEO","w":0.1109},"004468500":{"n":"Achieve Life Sciences Inc","t":"ACHV","w":0.0981},"786700104":{"n":"Sagimet Biosciences Inc A","t":"SGMT","w":0.09},"29089Q105":{"n":"Emergent Biosolutions Inc","t":"EBS","w":0.0856},"62855J104":{"n":"Myriad Genetics Inc","t":"MYGN","w":0.0856},"107924102":{"n":"Bridgebio Oncology Therapeut","t":"BBOT","w":0.0678},"56565P103":{"n":"Maplight Therapeutics Inc","t":"MPLT","w":0.0556},"829401108":{"n":"Sionna Therapeutics Inc","t":"SION","w":0.036}}}