QQQ vs XBI ETF holdings comparison
Invesco QQQ Trust (QQQ) · SPDR S&P Biotech ETF (XBI)
QQQ and XBI overlap by 3.6% by portfolio weight. The remaining 96.4 percentage points are not counted as shared holdings weight by this calculation. They share 6 stocks; the largest shared position is Amgen Inc. (AMGN), contributing 1.07% to the overlap.
The holdings dates differ. This can slightly understate overlap for funds tracking similar indexes.
What this means
QQQ and XBI share a smaller portion of their portfolio weight in the same underlying stocks. OverlapCheck labels this "low holdings overlap" using house ranges of 70% or more, 30% to under 70%, and under 30%. These descriptive ranges are not industry standards or investment guidance. Holdings overlap does not measure correlation, volatility, geographic or factor exposure, fees, or suitability.
Overlap by weight sums the smaller of the two funds' weights for every stock they both hold. It answers "how much of my money is in the same stocks either way?" See methodology.
This comparison covers normalized equity positions represented in the dataset. Cash, derivatives, options, structured notes, and other non-equity assets are not included, so the result is not a complete comparison of every asset or risk in either fund.
Top shared holdings
| Company | Ticker | in QQQ | in XBI |
|---|---|---|---|
| Amgen Inc. | AMGN | 1.07% | 1.16% |
| Gilead Sciences, Inc. | GILD | 0.98% | 1.08% |
| Vertex Pharmaceuticals Inc. | VRTX | 0.64% | 1.12% |
| Regeneron Pharmaceuticals, Inc. | REGN | 0.45% | 1.22% |
| Alnylam Pharmaceuticals, Inc. | ALNY | 0.25% | 0.73% |
| Insmed Inc. | INSM | 0.20% | 1.19% |
Holdings only in QQQ or XBI
QQQ has 95 fund-only positions representing approximately 96.3 percentage points of reported exposure; XBI has 141 fund-only positions representing approximately 93.4 percentage points of reported exposure. These are positions whose normalized security identifiers appear in one issuer file but not the other.
Largest positions only in QQQ
| Company | Ticker | Weight |
|---|---|---|
| NVIDIA Corp. | NVDA | 8.68% |
| Apple Inc. | AAPL | 7.63% |
| Microsoft Corp. | MSFT | 5.63% |
| Amazon.com, Inc. | AMZN | 4.58% |
| Tesla, Inc. | TSLA | 3.80% |
| Meta Platforms, Inc. | META | 3.46% |
| Walmart Inc. | WMT | 3.43% |
| Alphabet Inc. | GOOGL | 3.43% |
| Alphabet Inc. | GOOG | 3.20% |
| Broadcom Inc. | AVGO | 3.01% |
Largest positions only in XBI
| Company | Ticker | Weight |
|---|---|---|
| Moderna Inc | MRNA | 3.05% |
| Twist Bioscience Corp | TWST | 1.98% |
| Apogee Therapeutics Inc | APGE | 1.44% |
| Kymera Therapeutics Inc | KYMR | 1.43% |
| Oruka Therapeutics Inc | ORKA | 1.41% |
| Natera Inc | NTRA | 1.38% |
| Halozyme Therapeutics Inc | HALO | 1.37% |
| Praxis Precision Medicines I | PRAX | 1.35% |
| Dianthus Therapeutics Inc | DNTH | 1.30% |
| Revolution Medicines Inc | RVMD | 1.30% |
FAQ
How much do QQQ and XBI overlap?
QQQ and XBI have 3.6% overlap by weight, sharing 6 equity positions (out of 101 in QQQ and 147 in XBI). The official holdings files used are dated 2026-03-31 for QQQ and 2026-08-25 for XBI.
What does 3.6% overlap mean?
QQQ and XBI share a smaller portion of their portfolio weight in the same underlying stocks. OverlapCheck labels this "low holdings overlap" using house ranges of 70% or more, 30% to under 70%, and under 30%. These descriptive ranges are not industry standards or investment guidance. Holdings overlap does not measure correlation, volatility, geographic or factor exposure, fees, or suitability.
Which stocks do QQQ and XBI both hold?
The largest shared positions are Amgen Inc., Gilead Sciences, Inc., Vertex Pharmaceuticals Inc., Regeneron Pharmaceuticals, Inc., Alnylam Pharmaceuticals, Inc.. The top shared holdings with weights in each fund are shown on this page.
What holdings are different between QQQ and XBI?
QQQ has 95 positions not found in XBI, while XBI has 141 positions not found in QQQ. The largest fund-only positions and their weights are shown on this page.